Typhoid fever is a severe disease caused by the bacterium Salmonella enterica serotype Typhi (S. Typhi). It is a life-threatening illness, spread through contaminated food or water. The Center of Disease Control and Prevention (CDC) estimates typhoid fever affects 5,700 people in the United States each year. The vaccine for Typhoid is highly recommended for travelers to South Asia, especially Pakistan, India, and Bangladesh.
If contracted, typhoid fever can be treated with antibiotics, which can reduce complications and mortality rates associated with the disease. However, in recent years, the bacterium responsible for typhoid fever has become increasingly resistant to many antibiotics commonly used to treat the infection. This has made treatment more challenging and underscores the importance of appropriate diagnosis and antibiotic stewardship to help slow the development of antibiotic resistance.
The injection typhoid vaccine can be administered to anyone over the age of 2 years, and a single shot provides sufficient protection. It should be given at least one week before travel to areas where typhoid is a risk.